As a seasoned acupuncturist, Jenny-Marie Greenough, LAc has spent years advocating for balanced nutrition and holistic wellness for her patients. Yet, despite her expertise, she often found herself searching for more effective and sustainable dietary interventions. It wasn't until she personally embarked on the journey of a fast-mimicking diet (FMD) that she truly understood its transformative potential. Intrigued by the scientific promise of FMD, which mimics the beneficial effects of fasting while still allowing for some food intake, Jenny-Marie decided to integrate it into her own lifestyle. The results were remarkable: enhanced energy levels, improved metabolic markers, and a newfound sense of vitality.
Inspired by her (and her husband’s!) own experience, she began to introduce FMD to her patients, witnessing firsthand the profound impact it could have on their health and well-being.
(Information provided courtesy of Prolon and L-Nutra Health)
What is FMD?
Prolon’s fast-mimicking diet (FMD) has emerged as a revolutionary approach that combines the advantages of fasting with the ease of regular eating.
Discovered and developed at the Longevity Institute of the University of Southern California, Prolon’s technology is plant-based nutrition that allows the body to enter into a beneficial fasting state without triggering the cells’ nutrient sensors. As the name suggests, it mimics fasting…while still allowing you to eat food. This nourished fasting fine-tunes cells, supports healthy aging, and eliminates the need to do a water-only starvation fast, which can have negative side effects.
By simulating the effects of traditional fasting while allowing for the consumption of carefully selected & clinically-tested, tasty, high-quality foods, Prolon’s FMD offers a sustainable and less restrictive path to wellness!
This innovative dietary strategy has been shown to promote weight loss, enhance metabolic health, reduce inflammation, and even support cellular rejuvenation. As a result, more people are turning to FMD to harness the profound health benefits of fasting without the hardships typically associated with prolonged periods of complete food abstinence, or the expense and potential side-effects of some prescription drugs.
How does FMD compare to GLP-1s Like Ozempic and Wegovy?
With the increasing popularity of GLP-1s like Ozempic and Wegovy, it's essential to understand the comparative benefits and limitations of these treatments. While GLP-1s can be lifesaving for some, they have been sorely over-prescribed, and the negative side effects are becoming even clearer.
We offer nutrition-based programs that center around the science of the Fasting Mimicking Diet (FMD) to reverse diabetes and metabolic conditions. Unlike the continuous pharmaceutical interventions of GLP-1s, our programs use FMD in conjunction with dietetic guidance, university tested-protocol, and physician oversight to provide a non-invasive, 360-degree approach to address the root causes of metabolic conditions for a specified period of time. In comparing the differences between GLP-1s and our FMD-centered plans, the FMD’s benefits prove to offer a more manageable, sustainable, and root cause-centered solution to obesity, metabolic conditions, blood sugar management, and diabetes.
How They Work
The way in which GLP-1s and the FMD work within the body are vastly different. GLP-1s are pharmaceuticals that mimic the natural GLP-1 hormone, increasing insulin secretion (which pulls glucose into the cells), decreasing glucagon secretion (which breaks down glycogen in the liver), and slowing gastric emptying in the stomach (which ignites a feeling of fullness and satiety). The combination of its physiological mechanisms impact hormone levels to control appetite and glucose metabolism.
In contrast, the FMD works by mimicking the effects of a prolonged 5-day fast while still providing essential nutrients. This triggers autophagy, setting off a broad range of metabolic and cellular responses that have been shown, over time, to potentially reduce insulin levels, aid in better blood sugar control, promote fat-targeted weight loss (with preserved muscle mass), and improve overall metabolic health.
When FMD is delivered under the supervision of a doctor as part of a comprehensive lifestyle medicine program, diabetes medications can be safely de-prescribed towards diabetes remission. The FMD has also been shown to contribute to behavior change such as increased motivation both to exercise and to make better food and lifestyle choices, both essential for sustainable change.
Effects on Muscle Mass
Muscle mass plays a critical role in glucose management, as well as in the prevention and management of diabetes and other metabolic conditions. Muscle tissues are major sites for glucose uptake and storage, with higher muscle mass enhancing the body's capacity to store glucose, thereby improving insulin sensitivity and reducing the risk of insulin resistance. Since muscle tissue is metabolically active, increasing the basal metabolic rate (BMR = the number of calories needed to keep you alive) and aiding in weight management are crucial for sustained weight loss and diabetes prevention. Therefore, maintaining muscle mass is crucial in achieving sustained metabolic and weight management results.
One of the major benefits of FMD over GLP-1s is its muscle protection and preservation. While GLP1-s may be effective for weight loss, the use of these medications does not specifically target fat loss. In fact, up to 40% of the weight loss from GLP-1 use, on average, comes from the loss of lean tissue, including muscle mass. This is incredibly problematic for people who wish to eventually stop taking GLP-1s, as it can worsen body composition with each cycle; users may lose muscle while on GLP-1s and gain fat while off. The FMD, on the other hand, was specifically designed to preserve and protect lean body mass while targeting fat loss. Recent research shows no significant change in muscle mass during FMD use, which is crucial for maintaining metabolic health and physical function.
Administration
While GLP-1s are widely prescribed, their continuous use can pose challenges for many individuals. One of the main reasons for this is that treatments are continuous and require daily or weekly injections (some are available as oral tablets taken daily). These treatments require medical prescriptions and regular medical oversight to monitor efficacy and adjust dosages.
The FMD protocol itself, as part of a comprehensive program, offers a non-invasive, drug-free alternative that requires only five days of a dedicated eating plan per month for a recommended period (either four consecutive months in a six month program or six consecutive months in a twelve month). These programs are comprised of 360 degree support that is personalized, dietitian guided, and medically supervised, ensuring that participants are not only following the eating plan but are also educated and supported throughout their health journey; GLP-1 treatments, however, often leave patients without this level of comprehensive care or support - a major shortcoming. The L-Nutra Health Programs, using the FMD approach, offer a more user-friendly, less intrusive, and finite approach, compared to continuous pharmaceutical treatments that lack guidance or support.
Risks, Considerations, and Compliance
Potential risks and compliance issues can directly impact the safety, effectiveness, and sustainability of health strategies, affecting the long-term success of treatment. The common side effects of GLP-1s, which include nutritional deficiencies and gastrointestinal issues such as nausea, vomiting, changes in bowel habits, and potential risks for pancreatitis and gallbladder disease, may make its usage difficult to maintain or continue. Furthermore, strict compliance with medication schedules, lifestyle modifications, and regular medical supervision are crucial for the efficacy and safety of GLP-1s, also posing serious adherence challenges.
While the FMD requires a five-day commitment to a dedicated eating plan, which some may find challenging, it offers a user-friendly regimen, with dietitian-guided support. Easy-to-follow pre-packaged meal kits with the support of a dietitian coach make it convenient and manageable to incorporate into one’s lifestyle. During the five days, participants may experience hunger and fatigue, in addition to common symptoms that result from the body adapting to using different energy systems (like ketones) for fuel, such as headaches, dizziness, or difficulty concentrating; however, these side effects tend to lessen with repeated cycles as the body becomes more adept at burning fat and transitioning to ketosis.
Expense
Expense of a treatment directly affects an individual's ability to maintain it long-term, and cost is one of the major barriers for GLP-1s; without insurance, they range from $800 to $1,200 monthly, and shortages may potentially drive costs even higher. With insurance, copays vary widely, and additional costs include regular doctor's visits, potential side effect management, and supplementary medications or treatments. Furthermore, these costs are continual, as there is no set end date for treatment with GLP-1’s.
Our programs that incorporate the FMD, on other hand, range from $99 to $299 per month and have a set end date, after either six or twelve months. The monthly rate includes the FMD kits, dietitian oversight, quarterly lab tests and analysis, medical supervision (for type 2 diabetes) and more - with no added or hidden costs. Unlike GLP-1s, there are fixed, set time frames for these programs, making them a more financially predictable and manageable option; in knowing how long they will need to follow the protocol, participants are set up for a higher compliance and success rate.
For those struggling with blood sugar management, obesity, prediabetes, or diabetes, our L-Nutra Health Metabolic and Diabetes Remission and Regression Programs, which center around the power and science of the FMD, offer an effective, sustainable, non-invasive, and cost-efficient solution.
It Can Help With Depression too?
While psychotherapy and medication are mainstream treatments for depression, they don't always work for everyone. Let’s talk Fasting Mimicking Diet (FMD) and depression. Purposefully restricting food intake for periods of time may seem counterintuitive for your mental well-being; however, the Fasting Mimicking Diet (FMD) is generating buzz for its potential to amplify the effects of psychotherapy in battling depression.
The 5-Day FMD
Think of the FMD as a guided regimen that allows you to experience the benefits of fasting while still consuming specific micro- and macro-nutrients. Unlike water-only fasts which can leave you depleted, the FMD provides a science-backed formulated blend of nutrients delivered through food. This strategic nourishment "tricks" your body into a fasted state while avoiding the negative side effects of nutrient deprivation.
By flipping your metabolic switch into this fasted mode, the FMD is designed to promote cellular clean-up via autophagy and shift you into ketosis, a fat-burning state lauded for its brain-enhancing benefits. And the best part? You only have to follow the FMD protocol for 5 consecutive days per monthly cycle before returning to your regular diet.
The Surprising Study on FMD for Depression:
A groundbreaking randomized controlled trial published in the Journal of Clinical Psychology put the FMD to the test for depression. Twenty patients underwent 20 sessions of functional psychotherapy, a holistic mind-body approach. Half of the participants were also prescribed three consecutive cycles of the 5-day FMD regimen interspersed throughout their treatment.
The results were eye-opening. While both groups experienced relief from depressive symptoms post-treatment, those who combined psychotherapy with FMD saw significantly greater gains in self-esteem and psychological quality of life compared to psychotherapy alone.
Even more impressive - these added benefits stuck around during a 3-month follow-up!
Why the FMD May Amplify Psychotherapy's Impact
While this compelling pilot study was small in scale, the findings point to some powerful, potential avenues in which the FMD and psychotherapeutic interventions may be able to synergize:
Consulting with professionals to tailor a personalized approach is essential for achieving optimal outcomes—contact us now and begin your journey!
Disclaimer
The information provided is based on the personal experiences and professional opinions of Jenny-Marie Greenough LAc, who has successfully used and promoted the Fast Mimicking Diet (FMD) program. While Jenny-Marie has found significant benefits from this dietary approach, it is important to understand that individual results may vary.
This is intended for informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of your physician or other qualified health provider with any questions you may have regarding a medical condition or dietary regimen.
Jenny-Marie Greenough LAc/Raja Wellness, does not assume any responsibility for any potential adverse effects or consequences resulting from the use of the information presented herein. By following any dietary or health-related advice provided, you agree to do so at your own risk and acknowledge that any changes to your diet or lifestyle should be made in consultation with a healthcare professional.
In no event shall Jenny-Marie Greenough LAc/Raja Wellness be liable for any damages (including, without limitation, incidental and consequential damages, personal injury/wrongful death, lost profits, or damages resulting from the use or misuse of the information provided in this book). By reading this, you agree to indemnify and hold harmless Jenny-Marie Greenough LAc/Raja Wellness from and against any and all claims, actions, losses, damages, liabilities, and expenses (including attorneys’ fees) arising out of or in connection with your use of the information provided herein.
